Topical Sirolimus
Hyftor is a topical medication containing sirolimus 0.2%, used for treating facial angiofibromas associated with tuberous sclerosis complex (TSC). It is applied directly to the skin as a gel formulation, providing targeted treatment for this rare genetic condition that causes benign tumors to form on the face.
Hyftor is a topical sirolimus gel used to treat facial angiofibromas in patients with tuberous sclerosis complex.
Key facts at a glance
- RxNorm
- 2596865
- Generic
- Hyftor
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of facial angiofibromas associated with tuberous sclerosis complex (TSC) in adults and children 6 years of age and older. This rare genetic disorder causes non-cancerous tumors to develop on the skin, particularly the face.
Hyftor contains sirolimus (also known as rapamycin), which is an mTOR (mammalian target of rapamycin) inhibitor. The medication works by inhibiting cell proliferation and abnormal blood vessel growth that contribute to the formation of angiofibromas when applied topically to the affected areas.
Hyftor is for topical use only and should not be ingested or applied to mucous membranes. Common side effects may include skin irritation, dryness, or redness at the application site. Patients should avoid contact with eyes and mouth. As a prescription medication, it should only be used under the supervision of a healthcare provider familiar with the condition.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy