Hepatitis B Immune Globulin
Hyperhep B is a brand-name hyperimmune globulin product containing antibodies against the hepatitis B virus. It provides passive immunity and is used primarily for post-exposure prophylaxis in individuals who may have been exposed to hepatitis B, such as after needlestick injuries or sexual exposure, and for infants born to mothers with hepatitis B infection. This medication is typically administered by injection and is often given in conjunction with the hepatitis B vaccine series.
Hyperhep B is a hepatitis B hyperimmune globulin used for post-exposure prophylaxis against hepatitis B infection.
Key facts at a glance
- RxNorm
- 615872
- Generic
- Hyperhep B
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Post-exposure prophylaxis following needlestick injuries or other exposures to hepatitis B, prevention of hepatitis B transmission from infected mothers to newborns, and postexposure prevention in unvaccinated or incompletely vaccinated individuals with known or suspected exposure to hepatitis B virus.
Provides passive immunity by delivering pre-formed antibodies against hepatitis B surface antigen (HBsAg). These antibodies can neutralize the virus and help prevent infection until active immunity from vaccination develops.
Should be administered as soon as possible after exposure, ideally within 24-72 hours. Often given concurrently with hepatitis B vaccine for optimal protection. Contains human plasma and may carry risks of transfusion-transmitted infections. Use with caution in individuals with immunoglobulin A deficiency or thrombocytopenia. Medical supervision required for proper dosing and administration.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy