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Rho(D) Immune Globulin

Published: July 26, 2026Updated: July 26, 2026

Hyperrho is a brand-name Rho(D) immune globulin product used to prevent Rh isoimmunization in Rh-negative individuals who have been exposed to Rh-positive blood. It is primarily administered to pregnant Rh-negative women to protect their unborn babies from developing hemolytic disease.

Quick summary

Hyperrho is an Rh(D) immune globulin used to prevent Rh-negative mothers from developing antibodies against Rh-positive fetal blood cells.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
898569
Generic
Hyperrho
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Prevention of Rh isoimmunization in Rh-negative pregnant and postpartum women exposed to Rh-positive fetal blood; also used after miscarriage, abortion, or invasive procedures like amniocentesis to prevent maternal sensitization.

Provides passiveIgG antibodies that bind to Rh-positive red blood cells, preventing the Rh-negative person's immune system from recognizing and mounting an immune response against these foreign blood cells.

Administered by intramuscular injection typically at 28 weeks gestation and within 72 hours after delivery or sensitizing events. Not effective if patient is already sensitized. Contraindicated in Rh-positive patients and those with severe IgA deficiency.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy