Ifex
Ifex (ifosfamide) is a prescription chemotherapy medication used to treat various cancers, most commonly testicular cancer and certain soft tissue sarcomas. It belongs to a class of drugs called alkylating agents and works by interfering with cancer cell DNA to prevent their growth and division. This medication is typically administered intravenously by healthcare professionals in controlled clinical settings.
Ifex is an intravenous chemotherapy drug used to treat testicular cancer and other malignancies by damaging cancer cell DNA.
Key facts at a glance
- RxNorm
- 217701
- Generic
- Ifex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ifex is primarily used to treat testicular cancer (especially when other treatments have not been effective), as well as certain soft tissue sarcomas, Hodgkin's and non-Hodgkin's lymphomas, and other solid tumors. It may be used alone or in combination with other chemotherapy agents.
Ifex is an alkylating agent that works by binding to DNA strands and causing cross-linking, which prevents cancer cells from dividing and replicating. This interference with DNA function leads to cancer cell death. The drug is metabolized in the liver to its active form.
Ifex can cause significant side effects including hemorrhagic cystitis (bladder inflammation with bleeding), which is why the protective agent mesna is often given alongside it. Other serious risks include neurotoxicity, bone marrow suppression, and kidney toxicity. Adequate hydration is essential during treatment. Regular blood tests and monitoring are required throughout therapy.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy