Imidapril
Imidapril is an ACE inhibitor used primarily to treat hypertension and heart failure. It works by blocking an enzyme that causes blood vessels to narrow, allowing blood to flow more easily and reducing the heart's workload.
Imidapril is an ACE inhibitor that lowers blood pressure by relaxing blood vessels.
Key facts at a glance
- ATC
- C09AA16
- RxNorm
- 60245
- Generic
- Imidapril
- Class
- atc-c09
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 5-10mg once daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- not established
- Maximum
- consult physician
- Frequency
- N/A
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 2.5mg once daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
second third trimesterdiscontinue immediately
do not use during 2nd and 3rd trimesters due to risk of fetal renal failure oligohydramnios and death
immediate discontinuation and fetal assessment
Use of this medication in this population requires careful consideration of risks and benefits.
lactation
breastfeedingavoid
do not breastfeed while taking imidapril as it passes into breast milk
monitor infant for hypotension
Use of this medication in this population requires careful consideration of risks and benefits.
geriatric
elderly over 65start with lower dose
initiate therapy at low dose and titrate slowly due to increased sensitivity and higher risk of adverse effects
monitor blood pressure renal function and potassium levels closely
Use with caution and monitor for adverse effects.
pediatric_age
children adolescentsnot recommended
safety and efficacy not established in pediatric patients
not applicable
Use of this medication in this population requires careful consideration of risks and benefits.
renal_impairment
mild renal impairmentreduce initial dose
use lower initial dose and monitor renal function closely
monitor serum creatinine and potassium regularly
Use with caution and monitor for adverse effects.
renal_impairment
moderate severe renal impairmentsignificant dose reduction required
reduce dose significantly and monitor closely; avoid in severe impairment if possible
frequent monitoring of renal function electrolytes and urine output
Use with caution and monitor for adverse effects.
hepatic_impairment
mild moderate hepatic impairmentuse with caution
use with caution as imidapril is a prodrug requiring activation
monitor blood pressure and liver function tests
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class
Drug class information - Imidapril belongs to ACE inhibitors (C09AA06)
Common uses
Common therapeutic uses - used for essential hypertension and heart failure
Treatment of essential hypertension and heart failure. May also be used to slow the progression of diabetic nephropathy.
Imidapril is a prodrug that is converted to imidaprilat, which inhibits angiotensin-converting enzyme (ACE). This prevents the formation of angiotensin II, a potent vasoconstrictor, resulting in vasodilation and reduced blood pressure.
Common side effects include dry cough and dizziness. Contraindicated during pregnancy and in patients with a history of angioedema. May cause hyperkalemia, especially when combined with potassium-sparing diuretics. Blood pressure and kidney function should be monitored during treatment.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy