Imipenem
Imipenem is a broad-spectrum carbapenem antibiotic used to treat serious bacterial infections. The addition of cilastatin protects imipenem from breakdown in the kidneys, allowing higher concentrations to reach the site of infection.
A broad-spectrum antibiotic for serious infections, combined with a compound that protects it from kidney breakdown.
Key facts at a glance
- RxNorm
- 5690
- Generic
- Imipenem
- Class
- unclassified
- Brands
- Recarbrio, Primaxin
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats serious bacterial infections including respiratory tract infections, urinary tract infections, intra-abdominal infections, gynecologic infections, septicemia, and bone/joint infections.
Imipenem kills bacteria by inhibiting cell wall synthesis. Cilastatin inhibits renal dehydropeptidase, preventing breakdown of imipenem in the kidneys and allowing more active drug to reach the infection.
Reserved for serious infections when other antibiotics are unsuitable. Contraindicated in patients with penicillin allergy. Can cause seizures and other CNS effects, particularly with high doses or renal impairment. Requires dose adjustment in patients with reduced kidney function.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy