Imiquimod
Imiquimod is a topical immune response modifier cream used to treat certain skin conditions by stimulating the body's local immune system. It is prescribed for actinic keratosis (precancerous lesions on the face and scalp), superficial basal cell carcinoma, and external genital warts. The medication is applied directly to affected skin areas and works by enhancing immune responses at the application site.
Imiquimod is a topical immune response modifier cream used to treat precancerous skin lesions, certain skin cancers, and viral warts.
Key facts at a glance
- ATC
- D06BB10
- RxNorm
- 59943
- Generic
- Imiquimod
- Class
- atc-d06
- Brands
- Zyclara
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- cream
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Imiquimod is indicated for the treatment of actinic keratosis (AK) on the face and scalp, superficial basal cell carcinoma (sBCC), and external genital and perianal warts (condyloma acuminata).
The exact mechanism of action is unknown. Imiquimod is an immune response modifier that is believed to work by stimulating local cytokine production and enhancing innate and cell-mediated immune responses at the application site.
Imiquimod is for topical use only and should not be applied in or near the eyes, nose, or mouth. Common side effects include local skin reactions such as redness, swelling, itching, burning, and flaking at the application site. Treatment schedules vary by condition, and patients should follow their healthcare provider's instructions carefully. The medication may weaken latex condoms and diaphragms.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy