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Immunoglobulin G

Published: July 26, 2026Updated: August 25, 2026

Immunoglobulin G (IgG) is a class of antibodies that serves as a cornerstone of immune protection. As a medication, it provides passive immunity by supplementing the body's natural antibody defenses, making it essential for patients with immune deficiencies or certain autoimmune conditions.

Quick summary

Immunoglobulin G is a antibody treatment that boosts immune function in patients with immunodeficiency or autoimmune disorders.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy
BOXED WARNING

This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.

Key facts at a glance

ATC
J06BA
RxNorm
26744
Generic
Immunoglobulin G
Class
unclassified
Brands
Gammaked, Bivigam, Cuvitru, Panzyga, Asceniv, Cutaquig, Xembify, Octagam, Alyglo, Yimmugo, Qivigy, Gammagard ERC, Gammagard, Gamunex, Flebogamma
Availability
otc
Pregnancy
C
Lactation
safe
Half-life (h)
504
Onset (min)
30
Duration (h)
504
Routes
subcutaneous, intravenous
Forms
injectable solution, lyophilized powder for reconstitution
Regions
United States, Canada, European Union, United Kingdom, Australia, Japan
Monitoring
serum IgG trough levels, renal function, complete blood count, vital signs during infusion, signs of thrombosis or hemolysis

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used to treat primary and secondary immunodeficiencies, autoimmune conditions such as immune thrombocytopenic purpura (ITP) and chronic inflammatory demyelinating polyneuropathy (CIDP), certain neurological disorders like Guillain-Barré syndrome, Kawasaki disease, and severe infections in immunocompromised patients.

Provides passive immunity by delivering pooled antibodies from donated plasma, which helps neutralize pathogens, modulate immune system activity, and compensate for deficient antibody production in the recipient's body.

Administered via intravenous (IVIG) or subcutaneous (SCIG) infusion. Common side effects include infusion reactions such as headache, chills, and flu-like symptoms. As a blood-derived product, it undergoes rigorous screening for infectious agents. Requires appropriate medical supervision and monitoring during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy