Azathioprine
Imuran (azathioprine) is a prescription immunosuppressant medication that works by decreasing the activity of the immune system. It is used to prevent organ rejection in transplant patients and to treat certain autoimmune conditions such as rheumatoid arthritis, lupus, and inflammatory bowel disease.
Imuran is an immunosuppressant used to prevent organ rejection and treat autoimmune conditions by reducing immune system activity.
Key facts at a glance
- RxNorm
- 202559
- Generic
- Imuran
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Imuran is used to prevent rejection in patients who have received organ transplants (kidney, liver, heart, or lung). It is also prescribed for autoimmune conditions including rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Imuran is a purine synthesis inhibitor that interferes with the production of DNA and RNA in rapidly dividing cells, particularly immune cells (lymphocytes). By reducing the number and activity of these cells, it suppresses the immune response that could otherwise attack transplanted organs or cause autoimmune inflammation.
Imuran requires regular blood monitoring to check blood cell counts and liver function. It may increase the risk of infections and certain cancers due to immune suppression. Patients should avoid live vaccines while taking this medication and inform healthcare providers of all current medications, as many drugs can interact with azathioprine. Pregnant patients should discuss risks and benefits, as the medication may cause harm to an unborn baby.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy