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Influenza Vaccine

Published: July 22, 2026Updated: July 22, 2026

Influenza Vaccine is a preventive immunization that protects against seasonal influenza virus infections. It is recommended for most individuals, particularly those at higher risk of complications such as older adults, young children, pregnant women, and people with certain chronic medical conditions. Annual vaccination is advised since influenza strains change yearly and vaccine effectiveness varies by season.

Quick summary

Influenza Vaccine is a yearly immunization that protects against seasonal flu viruses by stimulating the immune system to produce antibodies.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 22, 2026Editorial policy

Key facts at a glance

ATC
J07BB02
Generic
Influenza Vaccine
Class
vaccine
Brands
Fluzone, Fluarix
Availability
behind_counter
Pregnancy
C
Lactation
safe
Onset (min)
10080
Routes
im, sc
Forms
injection
Regions
CN, US, EU, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)intramuscular injection
Usual dose
0.5mL (one dose)
Maximum
consult physician
Frequency
annually
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (6 months to 8 years (first time receiving))intramuscular injection
Usual dose
0.5mL (two doses, 4 weeks apart)
Maximum
consult physician
Frequency
annually after initial series
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (65 years and older (high-dose or adjuvanted))intramuscular injection
Usual dose
0.5mL (one dose)
Maximum
consult physician
Frequency
annually
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Influenza vaccines are not associated with toxic doses in traditional pharmaceutical sense; standard doses are based on immunogenicity rather than toxicity thresholds
Chronic overdose: N/A - vaccines are administered as single annual doses; repeated doses beyond recommended schedule may lead to increased adverse events rather than cumulative toxicity
Immediate actions
monitor for adverse reactions, contact healthcare provider, observe for allergic reactions including anaphylaxis
Antidote
N/A - no specific antidote exists; anaphylaxis may be treated with epinephrine(N/A)
Poison Control: 1-800-222-1222

Special Populations

7 groups
✓

pregnancy

all trimesters
safe
FDA Category
B
Dose Adjustment

standard dose recommended

Key Recommendations

CDC recommends influenza vaccination during any stage of pregnancy to protect both mother and fetus from influenza complications

Monitor

standard prenatal care

✓

lactation

breastfeeding mothers
safe
FDA Category
B
Dose Adjustment

standard dose recommended

Key Recommendations

influenza vaccine is safe for breastfeeding mothers and does not affect lactation

Monitor

none

✓

geriatric

65 years and older
safe
FDA Category
N
Dose Adjustment

high-dose or adjuvanted vaccine recommended

Key Recommendations

annual influenza vaccination strongly recommended using high-dose or adjuvanted formulations for enhanced immune response

Monitor

standard post-vaccination observation

✓

pediatric_age

6 months to 5 years
safe
FDA Category
N
Dose Adjustment

age-appropriate dosing required

Key Recommendations

annual influenza vaccination recommended for all children 6 months and older; some may require 2 doses initially

Monitor

standard post-vaccination observation

✓

renal_impairment

all stages
safe
FDA Category
N
Dose Adjustment

standard dose recommended

Key Recommendations

influenza vaccination is recommended for all patients with renal impairment including those on dialysis

Monitor

standard observation

✓

hepatic_impairment

all stages
safe
FDA Category
N
Dose Adjustment

standard dose recommended

Key Recommendations

influenza vaccination is recommended for patients with chronic liver disease

Monitor

standard observation

✓

other

immunocompromised
safe
FDA Category
N
Dose Adjustment

standard dose recommended

Key Recommendations

influenza vaccination is strongly recommended for immunocompromised patients; inactivated vaccine preferred over live attenuated

Monitor

standard observation

Statistics and clinical data

prescribingFDA
2023

First FDA approved influenza vaccine

Value:1930s

First influenza vaccine approved in the United States

drug_classWHO
2023

Drug class

Value:Vaccine - Influenza vaccine

Classification of influenza vaccines under ATC system

usageCDC
2023

Common uses

Value:Prevention of seasonal influenza

Primary indication for influenza vaccination

effectivenessCDC
2023

Vaccine effectiveness

Value:40-60%

Average effectiveness in reducing flu illness

Prevention of influenza virus infection. Recommended annually for all individuals 6 months and older, with particular emphasis for high-risk groups including seniors over 65, young children under 5, pregnant women, immunocompromised patients, and those with chronic conditions like asthma, diabetes, or heart disease.

The vaccine contains inactivated (killed) or attenuated (weakened) influenza virus antigens that stimulate the immune system to recognize and produce antibodies against circulating flu strains. This immune response allows the body to quickly fight off infection if exposed to the actual virus.

Administered annually before flu season (typically fall). Common mild side effects include soreness, redness, or swelling at the injection site, low-grade fever, and muscle aches. Severe allergic reactions are rare. The vaccine cannot cause influenza since it contains non-replicating or highly weakened virus. Effectiveness varies each season depending on how well the vaccine matches circulating strains.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy