Insulin Aspart, Human
Insulin Aspart, Human is a rapid-acting insulin analog used to improve glycemic control in adults and children with diabetes mellitus.
A rapid-acting insulin analog used to control blood sugar in people with diabetes, taken at mealtimes.
Key facts at a glance
- ATC
- A10AB05
- RxNorm
- 51428
- Generic
- Insulin Aspart, Human
- Class
- atc-a10
- Brands
- NovoLog Mix, Fiasp, Merilog, Kirsty, NovoLog
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution, suspension
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 0.5-1 unit/kg/day
- Maximum
- consult physician
- Frequency
- divided with meals
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 0.5-1 unit/kg/day
- Maximum
- consult physician
- Frequency
- divided with meals
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 0.3-0.5 unit/kg/day
- Maximum
- consult physician
- Frequency
- divided with meals
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
11 groupspregnancy
first trimesterindividualize dose based on blood glucose monitoring
insulin is preferred therapy for diabetes during pregnancy; use insulin aspart only when benefits outweigh risks
frequent blood glucose monitoring and fetal monitoring
Use with caution and monitor for adverse effects.
pregnancy
second trimesteradjust dose as pregnancy progresses typically increasing in second trimester
continue insulin therapy to maintain glycemic control
regular blood glucose monitoring and fetal growth assessments
Use with caution and monitor for adverse effects.
pregnancy
third trimestermay require dose adjustments near delivery
insulin requirements may change near delivery; coordinate with healthcare team
intensive blood glucose monitoring and fetal surveillance
Use with caution and monitor for adverse effects.
lactation
breastfeedingno specific adjustment needed
insulin aspart is compatible with breastfeeding; mothers should monitor blood glucose
monitor blood glucose to avoid hypoglycemia during breastfeeding sessions
pediatric_age
children 2 5 yearsstart at lower doses and titrate based on blood glucose response
use in pediatric patients with type 1 diabetes; requires careful supervision
frequent blood glucose monitoring especially during illness
Use with caution and monitor for adverse effects.
pediatric_age
children 6 12 yearsindividualize dose based on weight and blood glucose response
approved for use in pediatric patients age 2 years and older with type 1 diabetes
regular blood glucose monitoring and HbA1c assessments
Use with caution and monitor for adverse effects.
geriatric
elderly 65 years and olderstart with lower doses and titrate slowly; consider reduced insulin requirements
use with caution due to increased risk of hypoglycemia and comorbidities
frequent blood glucose monitoring and renal function assessment
Use with caution and monitor for adverse effects.
renal_impairment
mild renal impairmentmay require dose reduction due to decreased insulin clearance
monitor blood glucose closely and adjust dose as needed
regular monitoring of blood glucose and renal function
Use with caution and monitor for adverse effects.
renal_impairment
moderate to severe renal impairmentsignificant dose reduction often required; individualize based on monitoring
use with extreme caution; dose adjustment necessary due to reduced renal insulin clearance
frequent blood glucose monitoring and assessment of renal function
Use with caution and monitor for adverse effects.
hepatic_impairment
mild to moderate hepatic impairmentmay require dose adjustment due to altered insulin metabolism
use with caution; monitor blood glucose response closely
regular blood glucose monitoring and liver function tests
Use with caution and monitor for adverse effects.
hepatic_impairment
severe hepatic impairmentdose reduction often necessary; monitor closely
use with caution; liver plays role in glucose metabolism
frequent blood glucose monitoring and hepatic function assessment
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
FDA approval year for Insulin Aspart (NovoLog)
Drug class
ATC classification for Insulin Aspart
Common uses
Therapeutic indications for Insulin Aspart
Route of administration
Approved route of administration
Treatment of diabetes mellitus in adults and children, including Type 1 diabetes and Type 2 diabetes when insulin therapy is required for glycemic control.
Insulin aspart is a recombinant analog of human insulin that binds to insulin receptors on cells, promoting glucose uptake into tissues and suppressing hepatic glucose production, thereby lowering blood glucose levels. It has a faster onset and shorter duration compared to regular human insulin.
Should be administered within 5-10 minutes of starting a meal. Must be used as part of a comprehensive diabetes management plan including diet and exercise. Blood glucose monitoring is essential. Hypoglycemia is the most common adverse effect. Should not be used during episodes of hypoglycemia or in patients with hypersensitivity to insulin aspart or any excipients.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy