Insulin Icodec
Insulin Icodec, also known as Awiqli, is a novel once-weekly basal insulin analog designed to provide sustained blood glucose control over a 7-day period for patients with diabetes mellitus.
Insulin icodec is a once-weekly basal insulin injection that helps regulate blood sugar levels in people with diabetes by mimicking natural insulin activity.
Key facts at a glance
- ATC
- A10AE07
- RxNorm
- 2740394
- Generic
- Insulin Icodec
- Class
- atc-a10
- Brands
- Awiqli
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Insulin icodec is indicated for the treatment of diabetes mellitus in adults requiring insulin therapy, including both type 1 and type 2 diabetes. It is designed to provide basal glucose control as part of a complete diabetes management regimen that may include mealtime insulin, oral medications, or other injectable therapies.
Insulin icodec lowers blood glucose by stimulating peripheral glucose uptake, primarily in skeletal muscle and adipose tissue, and by inhibiting hepatic glucose production. As a long-acting insulin analog, it provides a steady release of insulin over approximately one week, maintaining consistent basal insulin levels without significant peaks.
Administered as a once-weekly subcutaneous injection; timing should remain consistent from week to week. Requires regular blood glucose monitoring to avoid hypoglycemia or hyperglycemia. Dose adjustments may be needed with changes in diet, physical activity, illness, or other medications. Not recommended for use in children or adolescents under 18 years of age. Must be stored properly and inspected before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy