Povidone-Iodine
Iopidine (apraclonidine) is a topical alpha-2 adrenergic agonist eye drop used to reduce elevated intraocular pressure in glaucoma and ocular hypertension patients. It works by decreasing aqueous humor production in the eye. This medication is particularly useful for patients who cannot tolerate beta-blocker eye drops.
Iopidine is an eye drop medication that lowers eye pressure in glaucoma patients by reducing fluid production in the eye.
Key facts at a glance
- RxNorm
- 151908
- Generic
- Iopidine
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Iopidine is used to treat open-angle glaucoma and ocular hypertension to lower intraocular pressure. It may also be used to reverse pharmacologically-induced mydriasis (pupil dilation) following eye examinations and to control intraoperative intraocular pressure spikes during ophthalmic surgery.
As an alpha-2 adrenergic agonist, Iopidine reduces intraocular pressure by decreasing aqueous humor production in the ciliary epithelium. It may also enhance uveoscleral outflow of aqueous fluid.
Common side effects include eye discomfort, dry mouth, and drowsiness. Iopidine should be used with caution in patients with severe cardiovascular disease, depression, or those taking MAO inhibitors. It may cause rebound hypertension if discontinued abruptly after prolonged use. Patients should not touch the dropper tip to any surface to avoid contamination.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy