Duloxetine
Irenka is a brand-name medication used to treat pseudobulbar affect (PBA), a neurological condition characterized by involuntary episodes of crying, laughing, or other emotional expressions that are disproportionate to the situation. It combines dextromethorphan with quinidine, working to help regulate emotional expression in the brain.
Irenka is a brand-name medication for pseudobulbar affect (PBA), helping to control involuntary emotional outbursts.
Key facts at a glance
- RxNorm
- 1652064
- Generic
- Irenka
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Irenka is primarily indicated for pseudobulbar affect (PBA), a condition resulting from neurological disorders such as ALS, multiple sclerosis, stroke, traumatic brain injury, or Parkinson's disease. It is not intended for cough suppression.
Irenka combines dextromethorphan, which acts on the brain's NMDA receptors and sigma-1 receptors to help regulate emotional expression, with quinidine, which inhibits the enzyme that breaks down dextromethorphan, thereby prolonging its therapeutic effect.
Irenka is contraindicated in patients with certain cardiac conditions, including QT prolongation and heart failure, due to the quinidine component. It may interact with numerous medications and should be used with caution. Common side effects may include dizziness, nausea, and somnolence. Patients should not exceed recommended doses.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy