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Irinotecan Liposomal

Published: July 26, 2026Updated: August 28, 2026

Irinotecan Liposomal is a chemotherapy medication that delivers irinotecan in a liposomal (fat-based) formulation to treat metastatic pancreatic cancer, typically used in combination with other chemotherapy agents. The liposomal delivery system helps improve drug stability and allows for targeted cancer cell destruction while potentially reducing side effects.

Quick summary

Irinotecan Liposomal is a topoisomerase I inhibitor chemotherapy used to treat metastatic pancreatic cancer, delivered via liposomes to enhance efficacy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1719768
Generic
Irinotecan Liposomal
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Metastatic pancreatic adenocarcinoma in patients who have previously received gemcitabine-based chemotherapy, administered in combination with 5-fluorouracil and leucovorin.

Once inside the body, the liposomal formulation releases irinotecan, which inhibits topoisomerase I—an enzyme critical for DNA replication and cell division—causing DNA damage and cancer cell death.

Requires IV infusion by a healthcare professional. Common side effects include diarrhea, nausea, vomiting, fatigue, and low blood cell counts. Premedication with anti-diarrheal medications may be recommended. Patients should be monitored closely for infusion reactions and severe diarrhea.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy