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Iron Sucrose

Published: July 26, 2026Updated: July 26, 2026

Iron sucrose is an intravenous iron supplement used to treat iron deficiency anemia. It provides iron directly to the bloodstream for transport to bone marrow, where it supports red blood cell production. This medication is commonly used when oral iron supplements are ineffective or not tolerated.

Quick summary

IV iron supplement for treating iron deficiency anemia when oral iron is not suitable.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

ATC
B03AB02
RxNorm
24909
Generic
Iron Sucrose
Class
atc-b03
Brands
Venofer
Availability
rx
Lactation
unknown
Routes
—
Forms
injection
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)IV
Usual dose
200mg iron once daily
Maximum
consult physician
Frequency
1-3 times per week
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)IV
Usual dose
3mg iron/kg (max 125mg)
Maximum
consult physician
Frequency
1-3 times per week
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)IV
Usual dose
200mg iron once daily
Maximum
consult physician
Frequency
1-3 times per week
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose that may cause serious toxicity
Chronic overdose: Cumulative doses exceeding 1000-2000 mg of elemental iron may lead to iron overload and related complications
Immediate actions
Supportive care, intravenous fluids, hemodynamic monitoring, consider chelation therapy with deferoxamine, gastric decontamination if oral ingestion
Antidote
Deferoxamine (chelating agent)(Effective for removing excess iron through chelation, most beneficial when administered promptly)
Poison Control: 1-800-222-1222

Special Populations

7 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

use only if benefits outweigh risks

Key Recommendations

avoid unless iron deficiency is severe and oral iron is not effective or tolerated

Monitor

regular fetal monitoring and maternal iron studies

Use with caution and monitor for adverse effects.

✓

pregnancy

second third trimester
safe
FDA Category
C
Dose Adjustment

standard dosing applies

Key Recommendations

considered safe for treatment of iron deficiency anemia when oral iron is ineffective

Monitor

monitor hemoglobin and ferritin levels

✓

lactation

safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

compatible with breastfeeding, minimal transfer to breast milk

Monitor

none specifically required

⚠

geriatric

elderly
caution
FDA Category
N
Dose Adjustment

start with lower dose, consider renal function

Key Recommendations

use with caution due to potential cardiovascular comorbidities

Monitor

monitor blood pressure, heart rate, and renal function

Use with caution and monitor for adverse effects.

⚠

pediatric_age

children 2 12 years
caution
FDA Category
C
Dose Adjustment

weight-based dosing required

Key Recommendations

use only when benefits outweigh risks, pediatric formulation preferred

Monitor

close monitoring of vital signs during infusion

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe ckl less than 30
caution
FDA Category
N
Dose Adjustment

reduce dose and frequency

Key Recommendations

use with caution in dialysis-dependent patients

Monitor

monitor renal function and iron parameters closely

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

severe
caution
FDA Category
N
Dose Adjustment

use with extreme caution

Key Recommendations

avoid in severe hepatic impairment unless benefits outweigh risks

Monitor

monitor liver function tests

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

FDA approval year

Value:2000

FDA approval date for Iron Sucrose (Venofer)

drug_classWHO
2023

Drug class

Value:Intravenous iron supplement

Pharmacological classification of Iron Sucrose

usageMedical guidelines
2023

Common uses

Value:Treatment of iron deficiency anemia in chronic kidney disease patients

Primary therapeutic indications for Iron Sucrose

Treatment of iron deficiency anemia in adults and children, particularly in patients with chronic kidney disease, inflammatory bowel disease, or other conditions where oral iron absorption is impaired or poorly tolerated.

Iron sucrose is administered intravenously where it dissociates into iron and sucrose. The iron then binds to transferrin and is transported to bone marrow erythroid precursor cells for incorporation into hemoglobin, supporting red blood cell production.

Administered only by healthcare professionals. Requires monitoring of iron parameters (ferritin, transferrin saturation). May cause hypersensitivity reactions including anaphylaxis. Contraindicated in anemia not caused by iron deficiency, iron overload conditions, or known hypersensitivity to the product.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy