Isosorbide Dinitrate
Isordil is a brand-name nitrate medication used to prevent and treat chest pain (angina). It works by relaxing and widening blood vessels, which improves blood flow to the heart and reduces its workload. This medication is typically prescribed for patients with coronary artery disease.
Isordil is a nitrate medication used to prevent or treat angina (chest pain) by widening blood vessels to improve heart blood flow.
Key facts at a glance
- RxNorm
- 151187
- Generic
- Isordil
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Isordil is primarily used to prevent and treat angina pectoris (chest pain) caused by coronary artery disease. It may also be used in acute settings to relieve anginal symptoms.
As a nitrate, Isordil releases nitric oxide which relaxes smooth muscle in blood vessel walls, causing vasodilation. This reduces the heart's workload by decreasing blood pressure and improving oxygen-rich blood flow to the heart muscle.
Isordil may cause headaches, dizziness, or flushing, especially when starting treatment. Tolerance can develop with continuous use, so dosing schedules often include a nitrate-free interval. Patients should avoid alcohol and inform their doctor of all medications, as interactions can occur.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy