Isoxsuprine
Isoxsuprine is a peripheral vasodilator medication that works by relaxing smooth muscle in blood vessels, improving blood flow to the extremities. It has historically been used to treat conditions involving poor peripheral circulation and was sometimes used for uterine relaxation during premature labor.
Isoxsuprine is a vasodilator used to improve blood flow in peripheral vascular conditions.
Key facts at a glance
- ATC
- C04AA01
- RxNorm
- 6066
- Generic
- Isoxsuprine
- Class
- atc-c04
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Isoxsuprine is used to treat peripheral vascular disorders associated with poor blood circulation, such as Raynaud's phenomenon, arteriosclerosis obliterans, and Buerger's disease. It has also been used off-label for preventing premature labor by relaxing the uterus.
Isoxsuprine acts as a beta-adrenergic agonist, causing relaxation of vascular smooth muscle and subsequent vasodilation. This improves blood flow, particularly to the extremities, and reduces peripheral vascular resistance.
Isoxsuprine is generally not considered a first-line treatment in many countries and has fallen out of common use. Common side effects may include hypotension, tachycardia, and flushing. It is contraindicated in patients with recent arterial bleeding or certain heart conditions. Use during pregnancy requires careful consideration of risks and benefits.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy