Ivermectin
Itovebi (inavolisib) is a prescription medication used to treat adults with hormone receptor (HR)-positive, HER2-negative breast cancer that has a PIK3CA mutation and has progressed after receiving endocrine therapy. It belongs to a class of drugs called PI3K inhibitors and is used in combination with other cancer medications.
Itovebi is a PI3K inhibitor used to treat certain types of advanced breast cancer with a PIK3CA mutation in combination with other therapies.
Key facts at a glance
- RxNorm
- 2695428
- Generic
- Itovebi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Itovebi is indicated for the treatment of HR-positive, HER2-negative breast cancer with a PIK3CA mutation in adults who have progressed after receiving endocrine-based therapy. It is used in combination with palbociclib and fulvestrant.
Itovebi is a PI3K inhibitor that targets and blocks the PI3K pathway, which is often overactive in breast cancers with PIK3CA mutations. By inhibiting this signaling pathway, it helps slow the growth and spread of cancer cells.
Common side effects may include high blood sugar, mouth sores, diarrhea, and blood disorders. Patients should be monitored for hyperglycemia and rash during treatment. This medication may cause fetal harm and should not be used during pregnancy. Regular blood tests are required during treatment to monitor blood cell counts and glucose levels.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy