Deferasirox
Jadenu (deferasirox) is an iron chelation medication used to treat chronic iron overload in patients with blood disorders requiring regular transfusions and in those with non-transfusion-dependent thalassemia. It works by binding to excess iron in the body, allowing it to be eliminated through urine and feces. This medication requires regular monitoring of liver and kidney function during treatment.
Jadenu is an iron-chelating agent used to reduce toxic iron levels in patients with chronic iron overload conditions.
Key facts at a glance
- RxNorm
- 1607785
- Generic
- Jadenu
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of chronic iron overload due to repeated blood transfusions in patients 2 years and older, and in patients with non-transfusion-dependent thalassemia syndromes aged 10 years and older.
Deferasirox is an iron chelator that selectively binds to iron, creating a stable complex that is then eliminated primarily through feces and urine, reducing total body iron burden.
Requires regular monitoring of serum creatinine, liver function, and auditory/ophthalmic examinations. May cause GI disturbances, skin rash, and rare but serious side effects including kidney impairment, liver failure, and GI bleeding. Should not be used in patients with severe kidney disease or certain blood disorders.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy