Mitomycin
Jelmyto is a prescription medication containing mitomycin formulated as a sterile gel for upper urinary tract instillation. It is specifically indicated for the treatment of low-grade upper tract urothelial carcinoma (LG-UTUC) in adults, offering a minimally invasive treatment option that is delivered directly into the renal pelvis and ureter.
Jelmyto is a topical chemotherapy gel used to treat low-grade upper tract urothelial carcinoma by direct instillation into the urinary tract.
Key facts at a glance
- RxNorm
- 2375819
- Generic
- Jelmyto
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Jelmyto is indicated for adults with low-grade upper tract urothelial carcinoma (LG-UTUC), a cancer of the lining of the urinary tract in the kidney and ureter.
Jelmyto contains mitomycin, an alkylating agent that works by cross-linking DNA in cancer cells, preventing them from dividing and multiplying. The gel formulation allows for prolonged contact with tumor tissue when instilled directly into the upper urinary tract.
Jelmyto is administered by qualified healthcare professionals via ureteral catheter. Patients should be monitored for ureteral obstruction, which is a potential adverse reaction. Common side effects may include urinary frequency, dysuria, hematuria, and flank pain. Women who are pregnant or breastfeeding should not handle this medication.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy