Lopinavir and Ritonavir
Kaletra is a prescription antiretroviral medication combining lopinavir and ritonavir, used in combination with other HIV medications to help control HIV-1 infection in adults and children. It belongs to a class of drugs called protease inhibitors and is typically prescribed when starting or changing HIV treatment regimens.
Kaletra is an HIV medication combining two protease inhibitors to suppress the virus when used with other antiretrovirals.
Key facts at a glance
- RxNorm
- 284756
- Generic
- Kaletra
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of HIV-1 infection in adults and children (14 days and older) in combination with other antiretroviral agents. It is not a cure for HIV but helps reduce viral load and improve immune function when used as part of a complete treatment regimen.
Kaletra contains two protease inhibitors: lopinavir inhibits the HIV protease enzyme, preventing the virus from producing infectious particles, while ritonavir boosts lopinavir levels by inhibiting its metabolism, allowing for more effective viral suppression.
Take exactly as prescribed with food. Common side effects include diarrhea, nausea, and stomach pain. May interact with many other medications including certain heart rhythm drugs, cholesterol medications, and seizure medications. Always inform healthcare providers of all current medications before starting Kaletra.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy