Cangrelor
Kengreal is an intravenous antiplatelet medication that works by blocking the P2Y12 ADP receptor on platelets, preventing blood clot formation. It is used as an adjunct to PCI (percutaneous coronary intervention) to reduce the risk of thrombotic events during the procedure in adults.
Kengreal is an IV antiplatelet drug used during heart procedures (PCI) to prevent dangerous blood clots.
Key facts at a glance
- RxNorm
- 1656057
- Generic
- Kengreal
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Kengreal is indicated to reduce the risk of thrombotic events (including stent thrombosis) in adults undergoing percutaneous coronary intervention (PCI) who have not been diagnosed with acute coronary syndrome (ACS).
Kengreal is a direct, competitive inhibitor of the P2Y12 ADP receptor on platelet surfaces. By blocking this receptor, it prevents ADP-mediated platelet activation and aggregation, reducing thrombus formation at the site of arterial injury during PCI.
Kengreal is administered intravenously by healthcare professionals in a hospital setting. Common side effects include bleeding, dyspnea, and thromboocytopenia. It should not be used in patients with significant active bleeding. Transitioning from other oral P2Y12 inhibitors to Kengreal should follow specific dosing protocols. Contraindicated in patients with severe hypersensitivity to the drug.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy