Ketotifen
Ketotifen is a second-generation antihistamine medication primarily used to treat allergic conditions such as allergic conjunctivitis (itchy, watery eyes) and allergic rhinitis (hay fever). It works by blocking histamine H1 receptors and stabilizing mast cells, preventing the release of inflammatory substances that cause allergic symptoms. The medication is available in both oral and ophthalmic (eye drop) formulations for convenient dosing based on the condition being treated.
Antihistamine medication for treating allergic eye conditions and hay fever symptoms.
Key facts at a glance
- ATC
- R06AX17
- RxNorm
- 6142
- Generic
- Ketotifen
- Class
- atc-r06
- Brands
- Wal-Zyr Itchy Eye, Zaditor, Alaway, Claritin Eye
- Availability
- otc
- Pregnancy
- C
- Lactation
- caution
- Half-life (h)
- 12
- Onset (min)
- 15
- Duration (h)
- 12
- Routes
- oral, ophthalmic
- Forms
- tablet, syrup, ophthalmic solution
- Regions
- United States, Canada, United Kingdom, Germany, France, Japan, Australia, India
- Monitoring
- liver function tests
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of allergic conjunctivitis (itchy, red, watery eyes), allergic rhinitis (hay fever), and prevention of asthma symptoms related to allergies. Ophthalmic formulation provides relief from seasonal eye allergies.
Acts as a histamine H1 receptor antagonist, blocking the action of histamine that triggers allergic symptoms. Additionally stabilizes mast cells, preventing them from releasing inflammatory mediators like histamine and other substances that cause allergic reactions.
May cause mild drowsiness or eye irritation depending on formulation. Contact lenses should be removed before applying eye drops and waited before reinserting. Patients with diabetes or history of seizures should use with caution. Always consult a healthcare provider before use during pregnancy or breastfeeding.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy