Sarilumab
Kevzara (sarilumab) is a prescription injection medication used to treat adults with moderate to severe rheumatoid arthritis who have not responded adequately to other therapies. It works by blocking interleukin-6 (IL-6), a protein that contributes to inflammation in the joints. This medication is typically used when methotrexate alone has not been effective or tolerated.
Kevzara is an injectable biologic medication for adults with moderate to severe rheumatoid arthritis that reduces inflammation by blocking IL-6 signaling.
Key facts at a glance
- RxNorm
- 1923334
- Generic
- Kevzara
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Kevzara is indicated for the treatment of moderate to severe rheumatoid arthritis in adult patients who have had an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs (DMARDs). It may be used as monotherapy or in combination with methotrexate or other conventional DMARDs.
Kevzara is a monoclonal antibody that binds to and blocks the interleukin-6 (IL-6) receptor. IL-6 is a pro-inflammatory cytokine that plays a key role in the inflammation, swelling, and joint damage associated with rheumatoid arthritis. By inhibiting IL-6 signaling, Kevzara helps reduce inflammation and disease activity.
Kevzara is administered by subcutaneous injection every other week. It may increase the risk of serious infections, including tuberculosis and invasive fungal infections. Patients should be screened for latent tuberculosis before starting treatment. Common side effects include injection site reactions, upper respiratory tract infections, and elevated cholesterol levels. Live vaccines should be avoided during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy