Desvenlafaxine
Khedezla (desvenlafaxine) is a brand-name serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant used to treat major depressive disorder in adults. It works by increasing levels of serotonin and norepinephrine in the brain, which are neurotransmitters associated with mood regulation.
Khedezla is an SNRI antidepressant used to treat major depressive disorder by affecting serotonin and norepinephrine levels.
Key facts at a glance
- RxNorm
- 1435475
- Generic
- Khedezla
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Khedezla is FDA-approved for the treatment of major depressive disorder (MDD) in adults. It may be prescribed when other treatments have not been effective or tolerated.
As an SNRI, Khedezla inhibits the reuptake of both serotonin and norepinephrine, increasing their availability in the brain. This action helps improve mood and emotional regulation in patients with depression.
Antidepressants including Khedezla carry a boxed warning for increased risk of suicidal thoughts and behaviors in young adults and adolescents. Discontinuation should be gradual under medical supervision. Common side effects may include nausea, dry mouth, and dizziness. Patients should not stop taking this medication without consulting their healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy