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Urokinase

Published: July 26, 2026Updated: July 26, 2026

Kinlytic is a brand-name thrombolytic medication used in hospital settings to dissolve harmful blood clots that can cause serious health complications. It works by activating the body's natural clot-dissolving system to break down fibrin in blood clots. This medication is typically reserved for serious, life-threatening clot-related emergencies.

Quick summary

Kinlytic is a hospital-administered thrombolytic drug that dissolves dangerous blood clots in conditions like pulmonary embolism.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
763567
Generic
Kinlytic
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Kinlytic is primarily used to treat acute, massive pulmonary embolism where clot dissolution may be life-saving. It may also be used to clear clogged intravenous catheters and has been used for certain cases of deep vein thrombosis in clinical practice.

Kinlytic contains urokinase, an enzyme that converts plasminogen to plasmin. Plasmin then breaks down fibrin—the protein mesh that holds blood clots together—effectively dissolving the clot and restoring normal blood flow.

This medication is administered intravenously in hospital settings under close medical supervision due to significant bleeding risks. It is contraindicated in patients with active bleeding, recent surgery, or history of hemorrhagic stroke. Treatment requires careful monitoring of clotting parameters and vital signs throughout the infusion period.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy