Sodium Polystyrene Sulfonate
Kionex (sodium polystyrene sulfonate) is a potassium-binding resin used to treat high potassium levels in the blood (hyperkalemia). It works by exchanging sodium ions for potassium ions in the intestines, helping the body remove excess potassium through bowel movements.
Kionex is a medication used to lower dangerously high potassium levels in the blood.
Key facts at a glance
- RxNorm
- 284757
- Generic
- Kionex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Kionex is primarily used to treat hyperkalemia, a condition characterized by elevated potassium levels in the blood that can cause dangerous heart rhythm abnormalities.
This medication binds to potassium in the gastrointestinal tract, exchanging sodium ions for potassium ions. The bound potassium is then eliminated from the body through stool.
Kionex may cause electrolyte imbalances, particularly low potassium (hypokalemia) or low sodium (hyponatremia). It should be used with caution in patients with heart failure, high blood pressure, or kidney disease. Common side effects include constipation, nausea, and loss of appetite. Always follow your healthcare provider's instructions regarding diet and other medications while taking this drug.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy