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Published: July 26, 2026Updated: July 26, 2026

Kisunla (donanemab-azbt) is a prescription medication approved for treating early symptomatic Alzheimer's disease in adults, including those with mild cognitive impairment or mild dementia due to Alzheimer's pathology. It is administered as an intravenous infusion, typically once every four weeks, and works by targeting and helping to reduce amyloid plaques in the brain.

Quick summary

Kisunla is an amyloid-targeting antibody therapy for early Alzheimer's disease that helps reduce brain amyloid plaques.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
2687974
Generic
Kisunla
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Kisunla is indicated for the treatment of early symptomatic Alzheimer's disease in adults, specifically those with mild cognitive impairment or mild dementia due to Alzheimer's disease who have confirmed presence of amyloid pathology.

Kisunla is a monoclonal antibody that targets and binds to amyloid-beta plaques (specifically N-terminal truncated and modified forms) in the brain. By binding to these plaques, it helps facilitate their removal through the immune system.

Kisunla requires regular intravenous infusions every four weeks. Common side effects include infusion-related reactions and amyloid-related imaging abnormalities (ARIA), which may present as brain swelling or microbleeds and require monitoring via MRI. Treatment decisions should involve discussion of individual benefits and risks with a healthcare provider.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy