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Kyprolis is a prescription proteasome inhibitor used to treat multiple myeloma, a cancer of plasma cells. It is typically prescribed for patients who have received prior therapy with other medications.
Kyprolis is an injectable cancer medication used to treat multiple myeloma in patients who have tried other treatments.
Key facts at a glance
- RxNorm
- 1302971
- Generic
- Kyprolis
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Kyprolis is indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, or who have demonstrated disease progression on or within 60 days of completing such therapy.
Kyprolis is a proteasome inhibitor that works by reversibly blocking the action of the proteasome, an enzyme complex responsible for breaking down proteins in cells. This leads to a buildup of proteins within cancer cells, ultimately causing cell death.
Kyprolis is administered as an intravenous infusion by a healthcare professional. Common side effects include fatigue, nausea, shortness of breath, diarrhea, and low blood cell counts. Patients should be monitored for heart failure, kidney problems, and other serious adverse reactions. Treatment should be managed by an oncologist experienced with multiple myeloma therapies.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy