Human Papillomavirus Vaccine, Type 18
The HPV Type 18 Vaccine is a prophylactic immunization that protects against infection by human papillomavirus type 18, a high-risk strain associated with cervical, anal, and oropharyngeal cancers. It is primarily recommended for adolescents and young adults before potential exposure to the virus. The vaccine uses virus-like particles (VLPs) composed of the L1 capsid protein to stimulate an immune response without containing live or inactivated virus.
A preventive vaccine against HPV type 18, a cancer-causing virus strain, given primarily to adolescents and young adults.
Key facts at a glance
- RxNorm
- 798266
- Generic
- L1 Protein, Human Papillomavirus Type 18 Vaccine
- Class
- unclassified
- Brands
- Gardasil 9, Gardasil
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe, injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of infections caused by human papillomavirus type 18, which is associated with cervical cancer, anal cancer, and other HPV-related malignancies. Recommended for routine immunization in adolescents and may be given to young adults who have not previously been vaccinated.
The vaccine contains L1 capsid proteins from HPV type 18 that self-assemble into virus-like particles (VLPs). These VLPs cannot cause infection but stimulate the immune system to produce antibodies that recognize and neutralize the actual HPV virus if encountered in the future.
This is a prophylactic vaccine and does not treat existing HPV infections or HPV-related diseases. It does not protect against all HPV types. Vaccination does not replace the need for regular cervical cancer screening (Pap smears/HPV testing). Consult healthcare provider for age-appropriate dosing schedules and to review any contraindications or allergy concerns.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy