Skip to content

Lactase

Published: July 26, 2026Updated: August 20, 2026

Lactase is an enzyme supplement that helps individuals digest lactose, the sugar found in milk and dairy products. It is primarily used by people with lactose intolerance.

Quick summary

Lactase is an enzyme supplement used to help people with lactose intolerance digest dairy products by breaking down the milk sugar lactose.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ATC
A09AA04
RxNorm
41397
Generic
Lactase
Class
atc-a09
Brands
Beano Dairy Defense, Lactaid
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet, capsule
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
500mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
250mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
400mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Lactase is generally recognized as safe (GRAS) by the FDA; no established toxic dose due to it being a naturally occurring digestive enzyme
Chronic overdose: No cumulative toxicity information available; lactase is not absorbed systemically and is excreted
Immediate actions
Discontinue supplement, maintain hydration, monitor for symptoms
Antidote
No specific antidote required(Supportive care only; enzyme is not absorbed)
Poison Control: 1-800-222-1222

Special Populations

8 groups
✓

pregnancy

first trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

use as directed with food when consuming dairy products

Monitor

standard prenatal care

✓

pregnancy

third trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

continue use as needed for lactose-containing foods

Monitor

standard prenatal care

✓

lactation

breastfeeding
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

safe to use when consuming dairy products while breastfeeding

Monitor

none required

⚠

pediatric_age

infants
caution
FDA Category
N
Dose Adjustment

use infant-specific formulations

Key Recommendations

consult pediatrician before use in infants under 2 years

Monitor

monitor for digestive symptoms

Use with caution and monitor for adverse effects.

✓

pediatric_age

children
safe
FDA Category
N
Dose Adjustment

use age-appropriate dosing

Key Recommendations

safe for children over 2 years when used as directed with dairy

Monitor

standard pediatric care

✓

geriatric

elderly
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

safe for use in elderly populations

Monitor

none required

✓

renal_impairment

mild to moderate
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

safe to use - not renally excreted

Monitor

none required

✓

hepatic_impairment

mild to moderate
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

safe to use - not hepatically metabolized

Monitor

none required

Statistics and clinical data

prescribingFDA
2023

Commonly prescribed since

Value:1970s

General prescribing information

drug_classWHO
2023

Drug class

Value:Digestive Enzyme Supplement

Drug class information

usageMedical guidelines
2023

Common uses

Value:Lactose intolerance treatment

Common therapeutic uses

mechanismPharmacology databases
2023

Mechanism of action

Value:Breaks down lactose into glucose and galactose

How the medication works

Lactase deficiency and lactose intolerance, allowing individuals to consume milk and dairy products without experiencing typical symptoms like bloating, gas, cramping, and diarrhea. It may also be used in infants with temporary lactase deficiency.

Lactase is an enzyme that hydrolyzes (breaks down) lactose into its two component sugars: glucose and galactose. These simpler sugars can then be easily absorbed by the small intestine. Taking lactase supplements with dairy foods provides the enzyme needed to complete this digestion process that the body cannot perform adequately on its own.

Lactase supplements should be taken at the start of consuming dairy products for best results. They are generally safe for most people but are not suitable for individuals with galactosemia. Effectiveness varies by person depending on the degree of lactase deficiency and the amount of dairy consumed. Always read product labeling as formulations and strengths may vary.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy