Terbinafine Hydrochloride
Lamisil Defense is a brand-name topical antifungal medication used to treat common skin infections such as athlete's foot, ringworm, and jock itch. It contains terbinafine as its active ingredient and is available over-the-counter for convenient at-home treatment of fungal skin conditions.
Lamisil Defense is a topical antifungal treatment for skin infections like athlete's foot and ringworm.
Key facts at a glance
- RxNorm
- 692846
- Generic
- Lamisil Defense
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lamisil Defense is indicated for the treatment of tinea corporis (ringworm), tinea cruris (jock itch), and tinea pedis (athlete's foot), including the interdigital and moccasin types. It is also used for pityriasis versicolor caused by Malassezia furfur.
As an allylamine antifungal, Lamisil Defense works by inhibiting the enzyme squalene epoxidase in fungal cells, which disrupts fungal cell membrane synthesis and leads to accumulation of squalene that is toxic to the fungus. This results in fungicidal activity against dermatophytes.
For external use only; avoid contact with eyes, nose, and mouth. Treatment duration varies by condition—athlete's foot typically requires 2-4 weeks, while ringworm and jock itch may require 1-2 weeks. Patients with chronic liver disease or immune disorders should consult a healthcare provider before use. Discontinue use and seek medical advice if no improvement occurs after the prescribed treatment period.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy