Landiolol
Landiolol is an ultra-short-acting, highly selective beta-1-adrenergic receptor antagonist used for rapid heart rate control in patients with atrial fibrillation, atrial flutter, and sinus tachycardia. It works by blocking the stimulating effects of catecholamines on the heart, slowing heart rate while having minimal impact on blood pressure and airway resistance.
A rapid-onset, selective beta-1 blocker for controlling heart rate in various cardiac arrhythmias.
Key facts at a glance
- ATC
- C07AB14
- RxNorm
- 2712070
- Generic
- Landiolol
- Class
- atc-c07
- Brands
- Rapiblyk
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Rapid rate control in atrial fibrillation, atrial flutter, and sinus tachycardia; particularly valuable in critical care and perioperative settings where precise heart rate management is needed.
Selectively blocks beta-1 receptors in the heart, inhibiting the positive chronotropic effects of catecholamines (epinephrine and norepinephrine), thereby reducing heart rate and cardiac oxygen demand without significant membrane-stabilizing activity.
Ultra-short acting allowing for rapid onset and offset of effects; highly cardioselective with minimal beta-2 activity; should be used cautiously in patients with bradycardia, AV block, or decompensated heart failure; requires continuous hemodynamic monitoring during administration.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy