Lasmiditan
Lasmiditan is a medication used to treat acute migraine attacks with or without aura in adults. It works by binding to and activating serotonin 5-HT1F receptors, which is believed to help relieve migraine symptoms. Unlike triptans, lasmiditan does not cause vasoconstriction, making it an option for some patients who cannot take other migraine medications.
Lasmiditan is an acute migraine treatment that works by activating 5-HT1F receptors to relieve migraine symptoms without causing vasoconstriction.
Key facts at a glance
- ATC
- N02CC08
- RxNorm
- 2256930
- Generic
- Lasmiditan
- Class
- atc-n02
- Brands
- Reyvow
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lasmiditan is indicated for the acute treatment of migraine with or without aura in adults. It is used to treat migraine attacks when they occur, not to prevent future migraines.
Lasmiditan is a selective agonist at the serotonin 5-HT1F receptor. By binding to these receptors, it is believed to reduce the transmission of pain signals and other migraine symptoms. The exact mechanism by which 5-HT1F receptor activation relieves migraine is not fully understood.
Lasmiditan can cause significant central nervous system side effects including dizziness, sedation, and numbness. Patients should not drive or operate machinery for at least 8 hours after taking lasmiditan. Unlike triptans, it does not constrict blood vessels, but should still be used with caution in patients with cardiovascular risk factors. Common side effects include dizziness, fatigue, and paresthesia.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy