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Latanoprost Eye Drops: Uses, Side Effects, and How to Use Them

Published: July 22, 2026Updated: July 22, 2026

Latanoprost is a prescription eye drop used to lower pressure inside the eye in people with open-angle glaucoma or high eye pressure. It may also be used off-label to help grow eyelashes, but you should use it for this purpose only if your doctor recommends it.

Quick summary

Use latanoprost exactly as prescribed, usually as one drop in the affected eye once daily. Contact your doctor or pharmacist if you have worsening redness, pain, discharge, or changes in your vision.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 22, 2026Editorial policy

Key facts at a glance

ATC
S01EE01
Generic
Latanoprost
Class
prostaglandin-analog
Brands
Xalatan
Availability
rx
Pregnancy
C
Lactation
caution
Half-life (h)
3
Duration (h)
24
Routes
ophthalmic
Forms
eye-drops
Regions
CN, US, EU, JP
Monitoring
eye-color-change

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)ophthalmic solution
Usual dose
1 drop
Maximum
consult physician
Frequency
once daily in the evening
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)ophthalmic solution
Usual dose
1 drop
Maximum
consult physician
Frequency
once daily in the evening
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)ophthalmic solution
Usual dose
1 drop
Maximum
consult physician
Frequency
once daily in the evening
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Dose that may cause significant systemic effects in adults
Chronic overdose: prolonged use exceeding recommended dosing may lead to cumulative ocular and systemic effects
Immediate actions
flush eyes with saline or water for 15 minutes, remove contact lenses, monitor vital signs
Antidote
no specific antidote(supportive care is mainstay of treatment)
Poison Control: 1-800-222-1222

Special Populations

8 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

Avoid use during pregnancy unless benefits significantly outweigh potential risks to fetus. Discuss with healthcare provider.

Monitor

regular fetal monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

second trimester
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

Use only if clearly needed; benefits vs risks should be assessed

Monitor

standard prenatal monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

Use only if benefits outweigh risks; consider alternatives

Monitor

fetal monitoring as indicated

Use with caution and monitor for adverse effects.

⚠

lactation

breastfeeding
caution
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

Use with caution; systemic absorption minimal but monitor infant

Monitor

monitor infant for adverse effects

Use with caution and monitor for adverse effects.

✗

pediatric_age

children under 18
unsafe
FDA Category
N
Dose Adjustment

not recommended

Key Recommendations

Not recommended for use in pediatric patients due to limited safety and efficacy data

Monitor

not applicable

Use of this medication in this population requires careful consideration of risks and benefits.

✓

geriatric

elderly 65 years
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

No dose adjustment required; monitor for increased sensitivity

Monitor

routine ocular pressure monitoring

✓

renal_impairment

mild to moderate
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

No dose adjustment required due to minimal systemic absorption

Monitor

routine monitoring

⚠

hepatic_impairment

mild to moderate
caution
FDA Category
N
Dose Adjustment

use with caution

Key Recommendations

Use with caution; metabolism may be altered; monitor response

Monitor

monitor therapeutic response

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingU.S. Food and Drug Administration
2023

FDA approval year

Value:1996

Year when latanoprost was first approved for medical use in the United States

drug_classAmerican Academy of Ophthalmology
2023

Drug class classification

Value:Prostaglandin analog

Latanoprost belongs to the prostaglandin analog class of medications

common_usesNational Library of Medicine
2023

Primary indications

Value:Open-angle glaucoma, Ocular hypertension

Main medical conditions treated with latanoprost eye drops

prescribingAmerican Academy of Ophthalmology
2023

First-line therapy status

Value:Recommended as first-line treatment

Latanoprost is recommended as a first-line medication for glaucoma management

Drug interactions

1 documented interaction(s) with other medications in this knowledge base.

CelecoxibMODERATE

NSAIDs(包括COX-2抑制剂)可能通过抑制内源性前列腺素合成而拮抗前列腺素类似物的降眼压作用,从而减弱latanoprost增加葡萄膜巩膜外流的疗效

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy