Lazertinib
Lazertinib is a targeted therapy medication that belongs to the EGFR tyrosine kinase inhibitor class. It is specifically designed to treat non-small cell lung cancer (NSCLC) in patients whose tumors have certain EGFR mutations, namely exon 19 deletions or exon 21 L858R substitution mutations. The medication works by selectively targeting these mutated cancer cells while sparing normal cells to a greater extent.
Lazertinib is an EGFR-targeted therapy for NSCLC patients with specific EGFR mutations.
Key facts at a glance
- ATC
- L01EB09
- RxNorm
- 2691150
- Generic
- Lazertinib
- Class
- atc-l01
- Brands
- Lazcluze
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lazertinib is indicated for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations, specifically exon 19 deletions and exon 21 L858R substitution mutations.
Lazertinib is a kinase inhibitor that targets and inhibits mutant forms of the epidermal growth factor receptor (EGFR). It selectively binds to EGFR with exon 19 deletions and exon 21 L858R substitutions at lower concentrations than wild-type (normal) EGFR, thereby inhibiting cancer cell proliferation.
As a targeted therapy, Lazertinib is only effective in patients whose tumors harbor the specific EGFR mutations it targets. Treatment should be initiated after confirmation of these mutations through appropriate testing. Common side effects may include skin reactions, diarrhea, and other EGFR inhibitor-related adverse events.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy