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Selpercatinib

Published: July 26, 2026Updated: July 26, 2026

Leqselvi (bimagrumab) is a brand-name medication that was developed as a human monoclonal antibody for the potential treatment of sporadic inclusion body myositis (sIBM), a rare progressive muscle disorder. The medication was under development by Novartis but development has since been discontinued.

Quick summary

Leqselvi was an investigational monoclonal antibody developed for sporadic inclusion body myositis that is no longer in development.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
2716564
Generic
Leqselvi
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Leqselvi was being investigated for the treatment of sporadic inclusion body myositis (sIBM), a rare inflammatory muscle disease that causes progressive muscle weakness and atrophy.

As a monoclonal antibody, Leqselvi worked by targeting specific proteins involved in muscle degeneration pathways, though the exact mechanism was not fully specified during development.

Leqselvi was an investigational medication that did not receive regulatory approval. Development has been discontinued. Patients should consult their healthcare provider for current treatment options for sIBM.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy