Chlorambucil
Leukeran (chlorambucil) is a prescription chemotherapy medication classified as an alkylating agent. It is used to treat certain cancers, primarily chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and non-Hodgkin lymphoma, by interfering with cancer cell DNA to slow or stop their growth and division.
Leukeran is a chemotherapy drug used to treat certain blood cancers by damaging cancer cell DNA.
Key facts at a glance
- RxNorm
- 202994
- Generic
- Leukeran
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Leukeran is primarily used to treat chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and certain types of non-Hodgkin lymphoma. It may also be used for other conditions as determined by an oncologist.
As an alkylating agent, Leukeran works by binding to cancer cell DNA, causing damage that interferes with the cell's ability to replicate. This leads to cell death, particularly affecting rapidly dividing cancer cells.
Leukeran suppresses bone marrow function, which can increase infection risk and cause anemia or bleeding problems. Regular blood monitoring is required during treatment. Common side effects include nausea, vomiting, and low blood counts. It may increase the risk of secondary cancers with long-term use. Should be used with caution in patients with impaired liver or kidney function.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy