Levobupivacaine
Levobupivacaine is a long-acting local anesthetic belonging to the amino amide class, used to provide regional anesthesia and pain relief during and after surgical procedures. It is commonly administered via epidural, intrathecal, or peripheral nerve block techniques to induce temporary loss of sensation in specific body areas.
Levobupivacaine is a long-acting local anesthetic used for surgical anesthesia and pain management via nerve blocks and epidural administration.
Key facts at a glance
- ATC
- N01BB10
- RxNorm
- 259453
- Generic
- Levobupivacaine
- Class
- atc-n01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Levobupivacaine is indicated for surgical anesthesia (including cesarean section when administered epidurally), postoperative pain management, labor analgesia, and prolonged peripheral nerve blocks. It is also used for chronic pain conditions when administered via continuous infusion techniques.
As a long-acting local anesthetic, levobupivacaine works by reversibly blocking voltage-gated sodium channels in nerve fibers, preventing the generation and conduction of nerve impulses. This results in temporary loss of sensation and motor function in the targeted area without affecting consciousness.
Levobupivacaine should only be administered by qualified healthcare professionals experienced in regional anesthesia techniques. It carries a risk of systemic toxicity if accidentally intravascular, and may cause cardiotoxicity at high doses. Caution is needed in patients with cardiovascular impairment, pregnancy (except labor), and elderly patients. The S-enantiomer form is considered to have a potentially improved safety profile compared to the racemic mixture.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy