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Levocarnitine

Published: July 26, 2026Updated: August 24, 2026

Levocarnitine is a naturally occurring amino acid derivative essential for energy metabolism, playing a crucial role in transporting fatty acids into mitochondria for energy production. It is primarily used to treat primary and secondary carnitine deficiency syndromes, which can result from genetic disorders, certain medications, or conditions like kidney disease requiring dialysis.

Quick summary

Levocarnitine is a supplement used to treat carnitine deficiency and support energy metabolism in patients with metabolic disorders.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 24, 2026Editorial policy

Key facts at a glance

ATC
A16AA01
RxNorm
42955
Generic
Levocarnitine
Class
atc-a16
Brands
Carni Q-Gel Forte, Carnitor
Availability
rx
Lactation
unknown
Routes
oral
Forms
injection, capsule, solution, tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
500mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
250mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
400mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose that may cause serious toxicity
Chronic overdose: Long-term use exceeding 3 grams daily may lead to cumulative toxicity
Immediate actions
Supportive care, gastric decontamination if recent ingestion, monitoring of vital signs
Antidote
No specific antidote available(Treatment is supportive and symptomatic)
Poison Control: 1-800-222-1222

Special Populations

8 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

use only if benefits outweigh potential risks to fetus

Monitor

regular fetal monitoring and obstetric evaluation

Use with caution and monitor for adverse effects.

⚠

pregnancy

second trimester
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

continue only if benefits outweigh risks

Monitor

routine prenatal monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

maintain therapeutic dose if needed

Key Recommendations

do not discontinue therapy if benefits outweigh risks

Monitor

fetal growth monitoring

Use with caution and monitor for adverse effects.

✓

lactation

breastfeeding
safe
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

compatible with breastfeeding, carnitine is naturally present in milk

Monitor

infant monitoring for adverse effects

✓

pediatric_age

neonates to adolescents
safe
FDA Category
C
Dose Adjustment

weight-based dosing

Key Recommendations

approved for primary and secondary carnitine deficiency in pediatric patients

Monitor

regular carnitine level monitoring, growth and development tracking

⚠

geriatric

elderly 65 years and older
caution
FDA Category
C
Dose Adjustment

adjust based on renal function

Key Recommendations

monitor renal function regularly, start with lower dose if renal impairment suspected

Monitor

renal function tests, carnitine levels

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe ckd and esrd
caution
FDA Category
C
Dose Adjustment

dose reduction required in severe impairment

Key Recommendations

monitor carnitine levels, avoid accumulation in ESRD patients not on dialysis

Monitor

regular serum carnitine monitoring, renal function tests

Use with caution and monitor for adverse effects.

✓

hepatic_impairment

mild to moderate
safe
FDA Category
C
Dose Adjustment

no specific adjustment needed

Key Recommendations

use standard dosing, monitor liver function

Monitor

liver function tests

Statistics and clinical data

prescribingFDA
2023

FDA approval year

Value:1992

Prescription levocarnitine (Carnitor) FDA approval year

drug_classFDA
2023

Drug class

Value:Amino acid derivative

Classification of Levocarnitine as an amino acid derivative supplement

usageMedical guidelines
2023

Primary indications

Value:Carnitine deficiency, metabolic disorders

Common therapeutic uses including primary and secondary carnitine deficiency

dosageDrug information
2023

Standard oral dose

Value:330-990 mg daily

Typical dosing range for oral levocarnitine supplementation

Treatment of primary systemic carnitine deficiency and secondary carnitine deficiency resulting from genetic disorders, metabolic conditions, kidney dialysis, or valproic acid toxicity. May also be used in patients with certain fatty acid oxidation disorders.

Levocarnitine acts as a cofactor essential for the transport of long-chain fatty acids across the inner mitochondrial membrane, enabling their conversion into energy through beta-oxidation. It also helps remove excess acyl groups from the body.

Available in oral and intravenous formulations. May cause gastrointestinal side effects such as nausea, diarrhea, or abdominal cramps. Patients with certain metabolic disorders or seizure conditions should use with caution. Regular monitoring of carnitine levels may be required during treatment.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy