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Mesalamine

Published: July 26, 2026Updated: July 26, 2026

Lialda is a brand-name prescription medication containing mesalamine, an anti-inflammatory drug used to treat inflammatory bowel diseases. It is primarily used to induce and maintain remission in patients with mild to moderate ulcerative colitis. The delayed-release formulation allows the medication to target inflammation directly in the colon.

Quick summary

Lialda is a colon-targeted anti-inflammatory medication used to treat ulcerative colitis by reducing inflammation in the large intestine.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
686430
Generic
Lialda
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Lialda is FDA-approved for the induction and maintenance of remission in patients with mild to moderate ulcerative colitis. It may also be used off-label for other inflammatory conditions affecting the colon.

Lialda contains mesalamine (5-aminosalicylic acid), which works locally in the colon to reduce inflammation. It inhibits inflammatory mediators and free radicals in the intestinal lining, helping to control symptoms such as rectal bleeding, diarrhea, and abdominal pain associated with ulcerative colitis.

Lialda is typically taken once daily with a meal. Patients with known kidney problems, stomach obstruction, or allergies to salicylates should use caution. Common side effects may include headache, nausea, and abdominal pain. Rare but serious side effects can include pancreatitis, hepatitis, and worsening of colitis. Regular monitoring by a healthcare provider is recommended during treatment.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy