Lindane
Lindane is a topical ectoparasiticide used primarily to treat scabies and lice infestations. It acts as a neurotoxin to parasites by disrupting their nervous system function. Due to its potential for serious neurotoxicity, it is generally reserved as a second-line treatment when first-line options are not suitable or have failed.
Lindane is a topical antiparasitic medication used for scabies and lice when other treatments cannot be used or have been ineffective.
Key facts at a glance
- ATC
- P03AB02
- RxNorm
- 1388
- Generic
- Lindane
- Class
- atc-p03
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lindane is used to treat infestations with scabies mites (Sarcoptes scabiei) and body lice (Pediculus corporis). It is typically prescribed when patients cannot tolerate first-line treatments like permethrin or malathion, or when those treatments have failed.
Lindane is an organochlorine compound that acts as a neurotoxin to arthropods and parasites. It disrupts normal nerve function in parasites by interfering with gamma-aminobutyric acid (GABA) receptors in their nervous systems, leading to paralysis and death of the parasites.
Due to neurotoxicity concerns, Lindane is restricted in many countries and available only through limited distribution programs in others. It should not be used in premature infants, young children, pregnant or nursing women, or patients with uncontrolled seizure disorders. Application must follow specific instructions to minimize systemic absorption and risk of adverse effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy