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Lisdexamfetamine Dimesylate

Published: July 26, 2026Updated: August 27, 2026

Lisdexamfetamine Dimesylate is a central nervous system stimulant that is converted to its active form in the body. It is primarily prescribed to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults, and is also FDA-approved for moderate-to-severe binge eating disorder in adults.

Quick summary

A stimulant medication used to treat ADHD and binge eating disorder by increasing dopamine and norepinephrine activity in the brain.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
673579
Generic
Lisdexamfetamine Dimesylate
Class
pin-variant
Brands
Arynta, Vyvanse
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Lisdexamfetamine is FDA-approved for treating ADHD in patients 6 years and older and for treating moderate-to-severe binge eating disorder in adults. It may also be used off-label for other conditions as determined by a healthcare provider.

This prodrug stimulant works by increasing the release of dopamine and norepinephrine in the brain, improving attention, focus, and impulse control in ADHD. The prodrug formulation provides a smoother, more controlled release of the active medication.

Common side effects include decreased appetite, insomnia, dry mouth, and increased heart rate. It has a high potential for abuse and dependence, and is classified as a Schedule II controlled substance. It should not be used in patients with cardiovascular disease, glaucoma, or those taking MAO inhibitors. Always follow prescribing instructions carefully.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy