Ritlecitinib
Litfulo is a prescription medication used to treat severe alopecia areata, an autoimmune condition that causes hair loss. It contains the active ingredient rixitrocel and is applied topically to the scalp. This treatment is approved for use in adults and adolescents meeting specific severity criteria.
Litfulo is a topical prescription medication for severe alopecia areata in adults and adolescents.
Key facts at a glance
- RxNorm
- 2641602
- Generic
- Litfulo
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Litfulo is indicated for the treatment of severe alopecia areata in adults and adolescents aged 12 years and older. Alopecia areata is an autoimmune condition where the immune system attacks hair follicles, leading to patchy or complete hair loss on the scalp, face, or body.
Litfulo contains rixitrocel, which is a Janus kinase (JAK) inhibitor. It works by targeting and inhibiting specific JAK enzymes involved in the inflammatory process that leads to hair follicle damage in alopecia areata. By reducing this inflammation, it may help promote hair regrowth.
Litfulo is for topical use only and should be applied exactly as prescribed by a healthcare provider. Common side effects may include application site reactions such as redness, itching, or acne. Patients should discuss their complete medical history, including current medications and any history of infections, with their doctor before starting treatment. Regular monitoring by a healthcare provider is important during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy