Luspatercept
Livdelzi (seladelpar) is a prescription brand-name medication used to treat primary biliary cholangitis (PBC), a chronic liver disease characterized by inflammation and damage to the small bile ducts. It is typically prescribed for adults who have had an inadequate response to standard therapy with ursodeoxycholic acid.
Livdelzi is a liver disease medication used to treat primary biliary cholangitis in adults who need additional therapy.
Key facts at a glance
- RxNorm
- 2690876
- Generic
- Livdelzi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Livdelzi is indicated for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) for adults with inadequate response to UDCA alone, or as monotherapy for those who cannot tolerate UDCA.
Livdelzi is a peroxisome proliferator-activated receptor delta (PPAR-delta) agonist. It works by activating PPAR-delta receptors, which helps reduce alkaline phosphatase (ALP) levels and may have anti-inflammatory effects in the liver.
Livdelzi is not recommended for patients with decompensated cirrhosis. Common side effects may include itching, headache, and abdominal pain. Patients should be monitored for liver function during treatment. This medication should only be prescribed by healthcare providers experienced in managing PBC.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy