Inotersen
Lodoco (colchicine 0.5mg) is a brand-name anti-inflammatory medication approved by the FDA in 2023 for reducing cardiovascular risk in adults with established atherosclerotic disease or multiple cardiovascular risk factors. It works by reducing inflammation in blood vessels, which is a key contributor to heart attacks, strokes, and other cardiovascular events.
Lodoco is a low-dose colchicine medication used to reduce heart attack, stroke, and cardiovascular death risk through its anti-inflammatory effects.
Key facts at a glance
- RxNorm
- 2663983
- Generic
- Lodoco
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Reduction of cardiovascular events (myocardial infarction, stroke, coronary revascularization, cardiovascular death) in adults with established atherosclerotic disease or multiple risk factors for cardiovascular disease.
Lodoco contains colchicine, an anti-inflammatory agent that inhibits microtubule polymerization, reducing neutrophil migration and activity, thereby decreasing vascular inflammation that contributes to atherosclerosis progression.
Common side effects include gastrointestinal symptoms such as diarrhea and abdominal pain. May interact with other medications metabolized by CYP3A4 or P-glycoprotein. Not recommended for patients with severe renal impairment. Should be used as directed by a healthcare provider for cardiovascular indications.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy