Gemfibrozil
Lopid (gemfibrozil) is a fibrate-class medication primarily used to treat elevated triglycerides and cholesterol levels in patients with lipid disorders. It works by reducing the production of triglycerides and increasing HDL ('good') cholesterol, typically prescribed when diet and exercise alone are insufficient.
Lopid is a cholesterol and triglyceride-lowering medication used to manage lipid disorders and reduce cardiovascular risk.
Key facts at a glance
- RxNorm
- 202999
- Generic
- Lopid
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lopid is used to treat hypertriglyceridemia (high triglycerides) and mixed dyslipidemia, helping to lower triglyceride levels and raise HDL cholesterol. It is prescribed when lifestyle modifications alone have not achieved adequate lipid control.
Lopid belongs to the fibrate drug class and works by activating peroxisome proliferator-activated receptor alpha (PPAR-α), which regulates lipid metabolism. This reduces hepatic triglyceride synthesis and secretion while increasing the breakdown of fatty acids.
Lopid should be used alongside diet and exercise modifications. Common side effects include gastrointestinal symptoms and muscle pain. Liver function tests should be monitored during treatment. Patients with liver, gallbladder, or severe kidney disease should use caution. There may be interactions with other lipid-lowering drugs, particularly statins, which may increase muscle-related risks.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy