Lorlatinib
Lorbrena is a prescription medication used to treat adults with a certain type of non-small cell lung cancer (NSCLC) that has spread to other parts of the body. It belongs to a class of drugs called kinase inhibitors and is specifically designed for patients whose tumors are ALK-positive.
Lorbrena is an ALK inhibitor used to treat ALK-positive non-small cell lung cancer that has spread.
Key facts at a glance
- RxNorm
- 2103170
- Generic
- Lorbrena
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lorbrena is indicated for the treatment of adults with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, typically after prior treatment with other ALK inhibitors.
As a kinase inhibitor, Lorbrena works by targeting and inhibiting ALK and ROS1 receptors, which are proteins that can drive the growth and spread of certain cancer cells.
Common side effects may include swelling, weight gain, numbness in joints or limbs, and mood changes. Patients should be monitored for liver problems and high cholesterol levels during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy