Lofexidine
Lucemyra (lofexidine) is a prescription medication that helps reduce opioid withdrawal symptoms in adults. It works by decreasing the release of norepinephrine in the body, which helps alleviate symptoms like anxiety, agitation, muscle aches, sweating, and nausea that occur when stopping opioid use. This medication is typically used as part of a comprehensive treatment program for opioid dependence.
Lucemyra is a medication that helps manage withdrawal symptoms when discontinuing opioid use.
Key facts at a glance
- RxNorm
- 2046592
- Generic
- Lucemyra
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lucemyra is used to treat physical withdrawal symptoms in adults undergoing discontinuation of opioids. It is not a treatment for opioid use disorder itself but helps manage acute withdrawal symptoms as part of a comprehensive treatment plan that may include counseling and behavioral therapy.
Lucemyra is an alpha-2 adrenergic agonist. It works by decreasing the activity of the sympathetic nervous system, reducing the release of norepinephrine. This helps alleviate withdrawal symptoms that occur due to increased sympathetic activity when opioids are stopped.
Lucemyra may cause low blood pressure, dizziness, and drowsiness. Patients should be monitored for cardiovascular effects. It is typically used for short-term treatment (up to 14 days). The medication should be part of a broader treatment program and should not be stopped abruptly without medical guidance. Patients should avoid driving or operating machinery until they know how the medication affects them.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy